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July 1964


Arch Dermatol. 1964;90(1):125-126. doi:10.1001/archderm.1964.01600010131038

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Case for Diagnosis: Juvenile Melanoma: Reticulohistiocytoma. Presented by Drs. Maurice J. Costello, and Charles P. DeFeo, Jr.  A healthy 37-year-old woman presented a lesion, 5 × 8 cm. It was a macular speckled nevus of the right thigh. Near the inferior pole of the nevus was a salmon-colored, asymptomatic, firm nodule, 1 × 2 cm, which had gradually evolved in the past six to twelve months. There are no other lesions present.Dr. Hyman suggested that she had a reticulohistiocytoma. Dr. Arthur Allen called it a juvenile melanoma, remarking that most so-called "solitary reticulohistiocytomas" are probably juvenile melanomas. Dr. Hyman disagreed with Dr. Allen noting that the cell type in this hematoxylin and eosin section is that of reticulohistiocytoma and that the section has none of the classic features of either of the cell types of juvenile melanoma (described by Allen and Spitz).Dr. Lever examined the slide. He thought

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