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July 1964


Arch Dermatol. 1964;90(1):126-127. doi:10.1001/archderm.1964.01600010132039

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Diagnosis: Lichen Spinulosus and Atrophic Alopecia (Syndrome of Lassueur-Graham Little). Presented by Drs. Norman B. Kanof and Saul Blau.  Fourteen years ago, a woman, now 57, developed pruritic papules in the right inguinal area which were associated with a thickening of the buccal mucosa and a vulval pruritus. Although no biopsy was done, a diagnosis of "characteristic lichen planus" was made in all three sites. Within three years, after several flares and remissions, all lesions cleared.Three years ago she developed a bilateral symmetrical eruption of the limbs which extended to include the axillae, lower abdomen, and pubic area. Oval groups of nonpruritic, skin-colored papules with spiny tips were scattered on the affected skin.Biopsy at this time was read as "may be lichen spinulosus."After one year of treatment with vitamin A, grenz radiation, oral steroids, and various topical remedies, the eruption cleared entirely.Six months ago, after a

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