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July 1964


Author Affiliations

Royal Infirmary of Edinburgh Skin Department Edinburgh, Scotland

Arch Dermatol. 1964;90(1):134. doi:10.1001/archderm.1964.01600010140042

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To the Editor:  I write with reference to the interesting paper by Donald Rosenthal and Thomas K. Burnham entitled "Nonthrombocytopenic Purpura Due to Carbromal Ingestion" (Arch Derm 89:200 [Feb] 1964).First, there is no doubt that such cases have been much more commonly seen in Britain than in the USA, but compared with the three cases mentioned as having been seen in the Dermatology Department of the Henry Ford Hospital in the last year, in this Department the numbers were as follows: 1961, two; 1962, four; 1963, three.Secondly, the authors state that "the only allergic reaction to Carbromal has been nonthrombocytopenic purpura. . . ." Although this is almost invariably the case, rarely a thrombocytopenic purpura can be caused by Carbromal, as witness this case history:"Mrs. X, aged 57, was referred to me on 29th January, 1964, for the diagnosis and treatment of a purpura, which was typical of a Carbromal

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