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Article
August 1964

Lichen Sclerosus et Atrophicus of the Vulva

Author Affiliations

LEYDEN, HOLLAND

From the Department of Dermatology, State University of Leyden, Holland. (Head: Prof. Dr. M. K. Polano).

Arch Dermatol. 1964;90(2):143-152. doi:10.1001/archderm.1964.01600020011002
Abstract

A report is given of the findings obtained in 55 female patients with lichen sclerosus et atrophicus. All but one had vulvar lesions; moreover, in the majority of the cases extravulvar lesions were noticed. No important differences could be detected between the so-called "kraurosis vulvae" (Breisky's disease) and lichen sclerosus et atrophicus of the vulva (LSAV). Hyperplastic changes in the vulvar epidermis were a common finding; the classification of these lesions is discussed. The results of some histochemical staining techniques showed an increase of hyaluronic acid containing ground-substance in LSAV. LSAV must be regarded as a precancerous condition. Nevertheless in noncomplicated cases as well as in LSAV associated with leukokeratosis, conservative treatment with corticosteroid ointments is recommended.

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