A report is given of the findings obtained in 55 female patients with lichen sclerosus et atrophicus. All but one had vulvar lesions; moreover, in the majority of the cases extravulvar lesions were noticed. No important differences could be detected between the so-called "kraurosis vulvae" (Breisky's disease) and lichen sclerosus et atrophicus of the vulva (LSAV). Hyperplastic changes in the vulvar epidermis were a common finding; the classification of these lesions is discussed. The results of some histochemical staining techniques showed an increase of hyaluronic acid containing ground-substance in LSAV. LSAV must be regarded as a precancerous condition. Nevertheless in noncomplicated cases as well as in LSAV associated with leukokeratosis, conservative treatment with corticosteroid ointments is recommended.
SUURMOND D. Lichen Sclerosus et Atrophicus of the Vulva. Arch Dermatol. 1964;90(2):143–152. doi:10.1001/archderm.1964.01600020011002
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