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August 1964


Arch Dermatol. 1964;90(2):241-242. doi:10.1001/archderm.1964.01600020109026

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Facial Granuloma? Presented by Dr. Maximilian E. Obermayer.  A 35-year-old patient has a progressive eruption, new lesions appearing and old ones extending. Discussion at a former presentation was inconclusive as to diagnosis and noncommittal as to therapy. The diagnosis of eosinophilic granuloma is said to have been advanced, but there is no record.The diagnosis of localized mastocytosis occurred to me because of a history of intermittent swelling and reddening of the lesions. Staining for mastocytes from the block of one of the previous biopsy specimens, as well as the recent one, showed only a few mast cells.The features of the recent biopsy point toward the diagnosis of facial granuloma.

Discussion  Dr. Maximilian E. Obermayer: Dr. S. W. Becker considered multiple facial granuloma the most likely diagnosis, lymphoblastoma a possibility, and mastocytosis unlikely.Dr. Paul Hirsch: The microscopic slides available for study at this meeting revealed a dense, polymorphic

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