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Article
September 1964

NEW ENGLAND DERMATOLOGICAL SOCIETY

Arch Dermatol. 1964;90(3):339-343. doi:10.1001/archderm.1964.01600030089020

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Abstract

Hyperthyroidism With Pretibial Myxedema. Presented by Dr. Edward Karian.  An American Negro woman aged 29 is presented. In March, 1961, a diagnosis of thyrotoxicosis was made, based on clinical symptoms, exophthalmos, enlarged thyroid gland, and elevation of the basal metabolic rate, protein bound iodine, and radioactive iodine uptake. Since that time the patient has been treated with propylthiouracil with good results.The patient was seen in the Skin Clinic in May, 1963, because of the presence of large indurated plaques on the legs, noted during the preceding two to three weeks.There are large infiltrated plaques on the anterolateral aspects of both legs. lesions are slightly erythematous, with accentuation of the hair follicles.On three occasions the lesion on the right was injected with multiple 0.1 cc doses of triamcinolone, The lesion on the left leg was treated with fluocinolone cream under occlusive (Saran wrap) dressings. Two months ago some

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