In a double-blind controlled clinical trial, phenoxybenzamine (Dibenzyline) and guanethidine were found to exert a remarkable antipruritic effect and to reduce the severity of the skin lesions in 26 patients suffering from atopic dermatitis.
VERMA BS, GULATI OD, GOKHALE SD, SHAH KC. Guanethidine and Phenoxybenzamine In Atopic Dermatitis: A Clinical Trial. Arch Dermatol. 1964;90(4):414–417. doi:10.1001/archderm.1964.01600040042009
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