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December 1964

Parenteral vs. Oral Folic Acid Antagonists

Arch Dermatol. 1964;90(6):553-557. doi:10.1001/archderm.1964.01600060019003

Parenteral methotrexate is an effective medication for controlling severe psoriasis.

The necessary clinical and laboratory precautions discussed above must be carefully followed.

Parenteral methotrexate was successful in patients in whom oral aminopterin or oral methotrexate did not clear the psoriatic lesion.