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January 1965


Arch Dermatol. 1965;91(1):90-91. doi:10.1001/archderm.1965.01600070096020

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Prurigo Nodularis. Presented by Max Popper, MD. 

History—  The patient is a 67-year-old Filipino who speaks very little English. His skin lesions were present for at least 16 years. He was seen first in March, 1962, and was treated for an exacerbation of his ailment on and off from March, 1962, to November, 1962. When he was first seen, there was oozing, pain, and considerable pruritus present.

Description of Lesions.—  Mostly on the extensor surfaces of arms and legs there are firm nodules which by confluence form sharply demarcated, hyperpigmented plaques. Lichenification is quite conspicuous in places. Considerable varicosities on legs are present.

Histology (Paul Hirsch, MD).—  The slide shows hyperkeratosis and parakeratosis overlying a hyperplastic epidermis. Cellular atypia is absent as the epidermis cells undergo an organized and essentially normal process of maturation. The stratum granulosum is preserved, and in some areas is relatively increased. Within the papilla are

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