The development of extensive sarcoid-like granulomas of glabrous skin as a result of allergic hypersensitivity to insoluble zirconium oxide is described and the subject discussed. In this case report, the lesions followed the use of a zirconium-containing topical preparation for the treatment of poison ivy dermatitis.
BALER GR. Granulomas From Topical Zirconium in Poison Ivy Dermatitis. Arch Dermatol. 1965;91(2):145–148. doi:10.1001/archderm.1965.01600080053009
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