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March 1965

The Epidermis

Arch Dermatol. 1965;91(3):287. doi:10.1001/archderm.1965.01600090095019

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As a source of information about the structure and function of the epidermis, this volume is a bonanza. As the editors state in their preface, "Never before has so much information been gathered on the subject." But the book is more than this. There is the excitement and stimulation of having a subject presented from so many points of view without loss of continuity. We thus view the epidermis through the eyes of the embryologist, the anatomist, the experimental biologist, the electron microscopist, the biochemist, the physical chemist, the microbiologist, the clinician, and even a dactylographist.

The book begins with a discussion of keratinization in historical perspective by the late Stephen Rothman to whom the book was appropriately dedicated. A highlight is Rothman's description of his response to the discovery of squalene in human skin surface fat. He immediately inferred that squalene was an intermediate in the biosynthesis of cholesterol

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