This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Malignant Acanthosis Nigricans. Presented by Dr. Helen O. Curth.
This is a follow-up presentation of a patient with acanthosis nigricans who is notable for (1) the clinical cutaneous appearance originally and ultimately, (2) a multiplicity of malignancies found upon an initial surgical exploration none of which retrospectively was deemed related to the dermatosis, (3) eventual discovery and eradication of a malignant tumor that is deemed related to the skin changes, and (4) improvement in the condition of the skin following eradication.The patient is a Negro male, now 84 years old, who was first seen several years ago when he showed skin changes of acanthosis nigricans of six months' duration on and about the lips, umbilicus, neck, and axillae. There also were keratoses on the elbows, knees, and palms. In mid-1961 two operations were performed, one for squamous cell carcinoma of the bladder and the second for a leiomyoma of
DERMATOLOGIC SOCIETY OF GREATER NEW YORK(formerly the Bronx Dermatological Society). Arch Dermatol. 1965;91(4):412–416. doi:10.1001/archderm.1965.01600100128032
Customize your JAMA Network experience by selecting one or more topics from the list below.