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May 1965

Water Soluble Antigens of Psoriatic Scale

Author Affiliations


From the Department of Dermatology, Montreal General Hospital. Dermatologist in Chief (Dr. Forsey); Research Fellow, Department of Dermatology (Dr. Haberman); Professor of Anatomy, McGill University (Dr. Langman).

Arch Dermatol. 1965;91(5):512-518. doi:10.1001/archderm.1965.01600110098019

Extracts of psoriatic scale were compared to extracts of nonpsoriatic exfoliative scale, plantar callus, normal epidermis, and to human serum by double diffusion in gel. Preliminary studies using agar electrophoresis and immunoelectrophoresis were also reported. Antigens identical to some of those in serum were present in all the extracts of exfoliative scale. An antigen was demonstrated in psoriatic scale which was not apparent in plantar callus or normal epidermis.

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