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June 1965


Arch Dermatol. 1965;91(6):681-683. doi:10.1001/archderm.1965.01600120113032

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Bowen's Disease. Presented by Dr. Charles Greenbaum.  The patient is an alert, elderly white man (aged 67) in apparent good health. A squamous-cell carcinoma in the scaphoid fossa of the left ear was removed in June 1963. Numerous actinic keratoses on the face and hands have been destroyed by curettage and electrocoagulation. Eight months ago, the patient developed a dusky red patch on the calf of one leg. The lesion has not changed significantly to date.

Dermatologic Examination.—  There is a sharply outlined plaque, 1.5 × 2.0 cm in diameter, on the calf of the left leg. The color is dull red and there is an area of infiltration at one edge, some of which has been removed for histologic examination.

Medical History.—  Inguinal herniorrhaphy was performed in June of 1964.

Biopsy Report.—  The biopsy report showed epithelial hyperplasia; hyperkeratosis; spotty parakeratosis; acanthosis; prickle cells which are enlarged, vacuolated, disorderly,

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