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July 1965


Arch Dermatol. 1965;92(1):110-113. doi:10.1001/archderm.1965.01600130116025

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Dysproteinemic Purpura. Presented by Dr. Harry J. Hurley.  This obese, 34-year-old white waitress is an orphan and has no knowledge of family history of any illnesses. In an auto accident four years ago, she sustained a fractured skull and had several subsequent convulsive seizures which were controlled with phenobarbital.Five years ago, the patient developed an erythematous maculopapular rash on her arms which was originally thought to be due to detergent contact. These lesions waxed and waned until three years ago when she noted facial involvement. Eight months later a similar eruption appeared on her legs and arms. When the erythema faded, it left a residual brownish hyperpigmentation which has lasted several months.Her general physical appearance is that of an obese white woman in no acute distress. On exertion, the patient rapidly develops patchy purpuric lesions on her arms and legs. Also, she presents a long-standing eczematous eruption of

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