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December 1965

Cutaneous Vascular Reactivity in Atopic Children

Author Affiliations


From the Section of Dermatology, Mayo Clinic and Mayo Foundation.

Arch Dermatol. 1965;92(6):621-624. doi:10.1001/archderm.1965.01600180013002

Twenty-one children having atopic dermatitis, underwent skin tests with 1:1,000 methacholine; 16 demonstrated the delayed-blanch phenomenon. Seven were studied for skin temperature responses and compared with seven nonatopic children. Atopic children have a lower basal skin temperature than nonatopic children. Exposure to a cold environment produced more rapid cooling of the fingers and toes of the atopic children. Some alterations in cutaneous vascular responsiveness are present to development of severe dermatitis.

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