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December 1965

Dermopathy in the Diabetic Syndrome

Author Affiliations


From the Department of Medicine, Section of Dermatology, Western Reserve University.

Arch Dermatol. 1965;92(6):625-634. doi:10.1001/archderm.1965.01600180017003

Dermopathy is the cutaneous manifestation of the microangiopathy of diabetes mellitus. A clinical survey of adults with known diabetes revealed a high frequency of dermopathy in those patients with retinopathy, neuropathy, and nephropathy. In early acute skin lesions, with no preceding trauma, there is acute inflammation and in some vesiculation of the skin. Ultimately in all lesions with slow healing, atrophy, fibrosis, and shallow scars develop. Histologically there was ateration of the collagen and small blood vessels. Correlation of dermopathy with necrobiosis lipoidica diabeticorum (NLD) is made by case reports. Dermopathy shows the same disease in the small blood vessels as does NLD. Dermopathy differs from NLD chiefly in the changes in the collagen.

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