This study confirms the findings of Beutner and Jordan that patients with pemphigus vulgaris have circulating serum antibodies demonstrable by indirect immunofluorescent staining to the intercellular areas of certain epithelial tissues, including skins.
Several technical considerations in immunofluorescent techniques may favor or diminish the likelihood of obtaining reproducible results, especially when skin is used as a substrate. These problems are discussed in some detail.
WALDORF DS, SMITH CW, STRAUSS AJL. Immunofluorescent Studies in Pemphigus Vulgaris: Confirmatory Observations and Evaluation of Technical Considerations. Arch Dermatol. 1966;93(1):28–33. doi:10.1001/archderm.1966.01600190034005
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: