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Article
February 1966

Idiopathic Guttate Hypomelanosis

Author Affiliations

NEW ORLEANS

From the Charity Hospital of Louisiana, Tulane University School of Medicine, and Louisiana State University School of Medicine, New Orleans.

Arch Dermatol. 1966;93(2):184-186. doi:10.1001/archderm.1966.01600200040005
Abstract

A new entity consisting of multiple, smooth, discrete, macular, off-white, hypopigmented lesions occurring on the upper and lower extremities and scattered areas on the trunk is described. By a random survey, the incidence of this dermatosis was found to be exceedingly high. Histologically, the skin appears normal except for the absence of melanin, and with the B-(3,4-dihydroxyphenyl)-L-alamine (dopa) stain there is decreased to absent dopa oxidase. Through analysis of patient histories, laboratory work, and a review of the literature a hypothesis as to etiology and relationship to other hypopigmenting disorders is discussed.

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