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February 1966

Malignant Change in Smallpox Vaccination Scars

Author Affiliations


From Instituto Portugues de Oncologia, Lisbon.

Arch Dermatol. 1966;93(2):229-230. doi:10.1001/archderm.1966.01600200085015

Seven cases of patients who had malignant change in smallpox vaccination scars have been previously published. This report is the eighth such case. The patient developed a pigmented basal-cell epithelioma in a vaccination scar 20 years after vaccination. Histological examination revealed a superficial basal-cell epithelioma.

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