Because most textbooks clearly state that knuckle pads do not occur on the thumbs, a patient with knuckle pads on the thumbs is reported. These are not simple reactions to trauma such as occupation. Their cause is unknown. The association of knuckle pads with other diseases and their occurrence on various well-known works of art are brought out to emphasize the need for us all to be observers.
ALLISON JR, ALLISON JR. Knuckle Pads. Arch Dermatol. 1966;93(3):311–316. doi:10.1001/archderm.1966.01600210047007
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