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March 1966

Blisters and the Basement Membrane in Relation to Age

Author Affiliations


From the Department of Dermatology and the Department of Pathology, University of Virginia School of Medicine, Charlottesville, Va.

Arch Dermatol. 1966;93(3):367-368. doi:10.1001/archderm.1966.01600210103021

The occurrence of blisters on the skin of infants with certain disorders which are not usually associated with bullae in older persons is a well-recognized, but poorly understood phenomenon. In the present investigation the morphology of the epidermal-dermal basement membrane and its immediate environs, where many of these bullae arise, was examined in various age groups in a search for clues which might conceivably aid in explaining this blister-prone tendency of young skin.

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