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March 1966


Arch Dermatol. 1966;93(3):374-379. doi:10.1001/archderm.1966.01600210110025

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Pemphigus Erythematosus. Presented by Rudolf L. Baer, MD, Rafael Andrade, MD, and Victor J. Selmanowitz, MD.  A 6-year-old white girl, began to develop skin changes on her back eight months ago. These persisted despite antibiotic and topical steroid therapy, while new lesions subsequently developed over widespread areas. No significant history of drug intake or contactants was elicited.On admission to University Hospital one month ago, the patient manifested irregularly bordered, erythematous, moist, crusted, scaly, 1 to 10 cm plaques on the face, neck, upper chest, back, umbilicus, and extremities. The scalp and nasolabial folds were covered with adherent, thick, grayish scales.

Biopsy.—  "There is acanthosis with areas of intra-epidermal cleavage in the superficial layers extending into the central portion of the rete ridges. There are numerous acantholytic cells, many of them showing fine basophilic granules in their cytoplasm. The horny layer is lamellated, thick, and contains some

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