Frequent use of night creams containing inorganic mercury salts may produce a distinctive discoloration of the face, usually limited to the folds of the skin and the eyelids. The pigmentation is due to deposition of mercury in the dermis, and histopathologically resembles a tattoo.
LAMAR LM, BLISS BO. Localized Pigmentation of the Skin Due to Topical Mercury. Arch Dermatol. 1966;93(4):450–453. doi:10.1001/archderm.1966.01600220062020
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