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May 1966


Arch Dermatol. 1966;93(5):625-629. doi:10.1001/archderm.1966.01600230129033

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Sjögren's Syndrome. Presented by Sam Atkinson, MD. 

Sites.—  Face and all four extremities.

Duration.—  3½ years.

History.—  This 56-year-old white woman developed ulcers over both lateral malleoli 3½ years ago. These ulcers were small, friable, bled easily, and as one would heal others would develop. No manner of treatment helped. One and one half years ago the patient noted itching, burning, and stinging of her eyes. A few months later she developed small erythematous papular lesions over both lower extremities from the thighs down to the areas of ulcerations. At about this time the patient noted dryness of mouth which she relieved by taking fluids. Six months ago prednisolone 15 mg per day resulted in some improvement of ulcers with no effect on the papular eruptions which had now spread to involve arms. Three months ago the patient noted morning pain and stiffness of her hands and

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