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June 1966

Underdevelopment of the Human Breast After Radiotherapy

Author Affiliations


From the department of dermatology (Drs. Weidman and Kopf) and surgery (Dr. Zimany), New York University School of Medicine, New York.

Arch Dermatol. 1966;93(6):708-710. doi:10.1001/archderm.1966.01600240074012

Gamma or x-radiation applied to the region of the female breast in the early years of life may result in underdevelopment of the mammae. Two patients are reported who were treated with radium emanation for cutaneous hemangiomas and suffered subsequent failure of proper development of breasts.

Since spontaneous involution of such hemangiomas does not result in breast atrophy, radiation therapy is of necessity implicated as the causative factor in this anatomical area and, therefore, should be avoided as a modality of treatment.