To the Editor:
As early as 1954, independent investigators reported on the use of dimethylpolysiloxane fluids, often referred to simply as silicone fluid, for soft tissue augmentation by injection techniques. Various reports in the literature and the lay press have described the use of pure silicone fluid or mixtures of silicone fluid and some other (usually secret) materials for mammary augmentation, treatment of facial hemiatrophy, wrinkle eradication, etc.The Dow Corning Center for Aid to Medical Research has been concerned about the problems involved by the rather indiscriminate injection of silicone fluids into people throughout the world. The articles in the lay press which have appeared since early 1965 have not diminished these problems.Silicones, alone or in combination with other materials, intended for injection into humans are considered as "new drugs" by the Federal Food and Drug Administration.1 At the present time any work involving silicone fluid injection
Braley S. CURRENT SITUATION ON THE USE OF DOW CORNING SILICONE FLUID FOR SOFT TISSUE AUGMENTATION BY INJECTION. Arch Dermatol. 1966;93(6):786. doi:10.1001/archderm.1966.01600240152032
Customize your JAMA Network experience by selecting one or more topics from the list below.