[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.237.138.69. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
June 1966

BIOLOGICAL FALSE-POSITIVE REACTIONS

Author Affiliations

University of Oregon Medical School 3181 SW Sam Jackson Park Rd Portland, Ore 97201

Arch Dermatol. 1966;93(6):786. doi:10.1001/archderm.1966.01600240152033

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:  In their recent article, Kwittken and Goldberg (Arch Derm93:177, 1966) considered their patient's weakly reactive venereal disease research laboratory test for syphilis (VDRL) and complement fixation tests to be biologic false-positive (BFP) reactions. This patient also had a positive Reiter protein complement fixation test, but the authors comment only that false-positive reactions can occur with this test. This is certainly true, but the diagnosis of BFP reaction must not be made unless the treponema pallidum immobilization (TPI) test or an equally specific test is negative and there is no historical or physical evidence of the presence of syphilis. The authors' failure to perform a TPI test in the 83-year-old patient is understandable, but their reasoning in making the diagnosis of BFP reaction is not.

First Page Preview View Large
First page PDF preview
First page PDF preview
×