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July 1966


Arch Dermatol. 1966;94(1):91-95. doi:10.1001/archderm.1966.01600250097022

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Cushing's Syndrome (Caused by Adrenocortical Hyperplasia) and Ulcers of the Legs. Presented by Dr. Conrad Stritzler, Dr. Ronald Stritzler, and Dr. Joseph Fishman.  A 33-year-old woman was apparently well until about ten years ago when menstruation ceased and Cushingoid stigmata began to develop (Fig 1). Since then slight trauma to the legs has resulted in ulcers that heal slowly. Three months ago she received a trivial injury to the right leg and a large stubborn ulcer developed (Fig 2).Physical examination now reveals, in addition to the ulcer, moon facies, malar cyanosis, hypertrichosis on the upper lip, and long purplish striae on the anterior aspects of the upper portions of the thighs. There are numerous

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