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July 1966

Lupus Erythematosus

Arch Dermatol. 1966;94(1):112. doi:10.1001/archderm.1966.01600250118032

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A masterful review by John Talbott of the historical background of lupus erythematosus (LE) sets the scene for this monograph, the first comprehensive and in-depth book on this complex disease and its many variants. The chapters range over the entire spectrum of LE, from the chronic discoid variety of cutaneous LE to the rapidly progressive and toxic syndrome of acute fulminating LE.

A distinguished group of contributors, all well qualified to write on their particular subject, have combined to make this an outstanding compendium on LE. The basic pathological patterns of systemic lupus erythematosus (SLE) are discussed by Bruce Cruickshank. Ian Mackay surveyed the current postulates on the autoimmune aspects of SLE including the forbidden clone hypothesis of Burnet. Peter Miescher, Naomi Rothfield, and Annatina Miescher reviewed the diverse immunologic phenomena of SLE, such as the occurrence of antinuclear antibodies, the abnormal immune reactions against the various types of blood

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