On two separate occasions a bright erythematous, maculopapular rash appeared in the same person within 12 hours after ingestion of a tablet containing 6 mg of dexbrompheniramine maleate, an antihistamine, and 120 mg of pseudoephedrine sulfate. The sequence of events strongly incriminated the antihistamine as the cause of the rash, especially since the subsequent ingestion of pseudoephedrine produced no untoward response. This is the first reported case of cutaneous reaction to dexbrompheniramine maleate.
SMITH G, FRED HL. Cutaneous Reaction to Dexbrompheniramine Maleate. Arch Dermatol. 1966;94(2):200. doi:10.1001/archderm.1966.01600260092013
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: