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August 1966

Cutaneous Reaction to Dexbrompheniramine Maleate

Author Affiliations


From the Department of Internal Medicine, Baylor University College of Medicine, and Ben Taub General Hospital, Houston.

Arch Dermatol. 1966;94(2):200. doi:10.1001/archderm.1966.01600260092013

On two separate occasions a bright erythematous, maculopapular rash appeared in the same person within 12 hours after ingestion of a tablet containing 6 mg of dexbrompheniramine maleate, an antihistamine, and 120 mg of pseudoephedrine sulfate. The sequence of events strongly incriminated the antihistamine as the cause of the rash, especially since the subsequent ingestion of pseudoephedrine produced no untoward response. This is the first reported case of cutaneous reaction to dexbrompheniramine maleate.

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