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Dermatitis Herpetiformis and Hypothyroidism. Presented by Adolph Rostenberg, Jr., MD, David Fretzin, MD, and Dean Dimmick, MD.
The patient is a 47-year-old married male, electrician, on whom in 1959, following symptoms of fatigue, weight gain, and hoarseness of voice, a diagnosis of hypothyroidism was made. He was placed on thyroid extract with clinical improvement within four weeks. However, by the sixth week he had developed a pruritic vesiculobullous eruption over the extensor surfaces of his arms and legs, with some lesions of the scalp and neck. This was initially felt to be a drug reaction from the thyroid medication, and the thyroid extract was discontinued, with clearing of the skin lesions. One month later he was given a trial of thyroglobulin (Proloid) with the development of the same skin lesions in four to six weeks. These again cleared with discontinuation of the thyroid medication. Subsequent trials of
CHICAGO DERMATOLOGICAL SOCIETY. Arch Dermatol. 1966;94(2):236–249. doi:10.1001/archderm.1966.01600260128022
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