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November 1966

Localized SclerodermaA Histochemical and Chemical Study

Arch Dermatol. 1966;94(5):531-535. doi:10.1001/archderm.1966.01600290005001

A case of linear and morphea scleroderma is reported. Histochemical studies revealed an increase of positive PAS material, diastase resistant, in the areas of homogenized collagen. Chemical analysis suggests an increase in hexoses and hexosamines, probably bound to the collagen fibers.