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April 1967

Progress in Allergy

Arch Dermatol. 1967;95(4):425. doi:10.1001/archderm.1967.01600340085022

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This well-organized book consists of an introduction by Waksman and five sophisticated sections on different immunologic subjects by various authors. In each section there is an extensive review of experimental work that has been done and the various theories that have been proposed together with the author's analysis and conclusions.

The sections are as follows: 1. "Proliferative and Differentiative Manifestations of Cellular Immune Potential" by Makinodan and Albright. The existence of pluripotential progenitors (probably not small lymphocytes) of antibody-forming cells is suggested.

2. "The Kinetics of Antibody Formation" by Uhr and Finkelstein. The differences between 19S and 7S antibody formation are discussed. The fact that 7S antibody-forming cells do not appear to require persisting antigen for continued antibody production, while 19S antibody producing cells do, may be due to the more effective binding of antigen by the 7S-producing cells. Thus 7S-producing cells may require only one molecule of antigen per

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