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May 1967

Calcinosis Cutis With Laser Microprobe Analysis: Report of a Self-Induced Case With Repeated Reproduction of Lesions

Author Affiliations

Cincinnati; Waltham, Mass

From the Department of Dermatology, College of Medicine, University of Cincinnati (Drs. Wilson and Goldman), the Laser Laboratory, Children's Hospital Research Foundation, Cincinnati (Dr. Goldman), and the Jarrell-Ash Company (Dr. Brech).

Arch Dermatol. 1967;95(5):490-495. doi:10.1001/archderm.1967.01600350052009

A psychiatric patient with a poison-ivy dermatitis was treated with chloride of lime and severe calcinosis cutis developed in the lesions. It was possible to reproduce these lesions of calcinosis in this patient. Calcium was identified both by laser spectroscopy and by histochemical studies. Because of the minute amount of tissue required for laser spectroscopy, biopsies both of lesions and of controls of normal skin were able to be processed for routine histological and histochemical studies after spectroscopy had been done on this same portion of tissue.

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