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August 1967


Arch Dermatol. 1967;96(2):217-224. doi:10.1001/archderm.1967.01610020109033

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Albopapuloid of Pasini (a Finding Associated with Epidermolysis Bullosa). Presented by Arthur B. Hyman, MD.  A 30-year-old woman has had a bullous dermatosis since birth. The parts most affected have been the dorsa of the hands, the legs, thighs, and lower part of the sacrum. In some areas the lesions have left the skin thin and glossy like that resulting from acrodermatitis chronica atrophicans. Several fingernails have disappeared nearly completely and have been replaced by shrivelled scar tissue.Examination of the rest of the skin reveals, on the posterior aspect of the neck between the scapula and on the sacrum, split-pea-sized, asymptomatic, discrete but closely set papules colored like the rest of the skin. These lesions were not preceded by bullae. Many have a wrinkled surface reminiscent of crumpled cigarette paper (Fig 1 and 2). The histopathology of the papules is as follows: With hematoxylin and eosin staining, the dermo-epidermal line is straightened. The upper cutis is abnormal in that

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