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September 1967

The Evolution of Concepts of Melanin Biology

Author Affiliations


From the Department of Dermatology, Harvard Medical School, Boston. Dr. Ishikawa is now with the Department of Biochemistry, Niigata University School of Medicine, Niigata, Japan.

Arch Dermatol. 1967;96(3):305-323. doi:10.1001/archderm.1967.01610030083015

Investigations of the biology of melanin have increased in number and diversity during the last decade. Melanocytes, the cellular units of melanin formation, are easily identified by light and electron microscopy and can be grown in tissue culture. Studies of melanocytes have clinical significance because problems associated with melanocytic changes are constantly encountered in internal medicine, surgery, pediatrics, and neurology, as well as in dermatology.

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