We have reviewed 1,135 biopsied neoplastic and nonneoplastic oral and pharyngeal lesions involving the following species: canine (1,002), bovine (15), feline (62), equine (50), ovine (5), and porcine (1). Among nonneoplastic conditions were pyogenic granuloma, actinomycosis, actinobacillosis, eosinophilic granuloma, trichinosis, and globidiosis. Benign neoplastic lesions included fibromatous epulis of periodontal origin, canine oral papillomatosis, fibroma, neurofibroma, lipoma, sebaceous adenoma, transmissible reticulum-cell tumor, and melanocytic nevus.
Among malignant oral neoplasms, the most common was canine malignant melanoma. Other malignancies included squamous cell carcinoma, basal cell epithelioma, mast cell sarcoma, fibrosarcoma, and rhabdomyosarcoma. The incidence, clinical features, and macroscopic and microscopic nature of the lesions have been delineated.
Gorlin RJ, Peterson WC. Oral Disease in Man and Animals: Based on Analysis of 1,135 Cases in a Variety of Species. Arch Dermatol. 1967;96(4):390–403. doi:10.1001/archderm.1967.01610040040009
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