A 46-year-old man having multiple myeloma developed cutaneous nodules and large cervical and mediastinal extramedullary plasmacytomas while being treated with phenylalanine mustard. The tumors progressed to a size producing tracheal and superior vena caval obstruction and spinal cord compression. They responded to phenylalanine mustard and radiation therapy. The myeloma cells were best identified by examination of Wright-stained smears obtained by needle aspiration of the tumor nodules.
Levin HA, Freeman RG, Smith FE, Lane M. Multiple Extramedullary Plasmacytomas. Arch Dermatol. 1967;96(4):456–461. doi:10.1001/archderm.1967.01610040106020
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