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October 1967

Multiple Extramedullary Plasmacytomas

Author Affiliations


From the departments of pharmacology (Drs. Levin, Smith, and Lane), dermatology (Dr. Freeman), and medicine (Drs. Smith and Lane), Baylor University College of Medicine, Houston. Dr. Levin is a fellow in chemotherapy.

Arch Dermatol. 1967;96(4):456-461. doi:10.1001/archderm.1967.01610040106020

A 46-year-old man having multiple myeloma developed cutaneous nodules and large cervical and mediastinal extramedullary plasmacytomas while being treated with phenylalanine mustard. The tumors progressed to a size producing tracheal and superior vena caval obstruction and spinal cord compression. They responded to phenylalanine mustard and radiation therapy. The myeloma cells were best identified by examination of Wright-stained smears obtained by needle aspiration of the tumor nodules.

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