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October 1967


Arch Dermatol. 1967;96(4):474-476. doi:10.1001/archderm.1967.01610040124024

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Discoid Lupus Erythematosus With Keratosis and Keratoacanthoma in the Center of the Area. Presented by Charles P. DeFeo, MD.  A 55-year-old white man has suffered from discoid lupus erythematosus for the past 33 years. In the past 20 years, he has had no therapy for this condition. Approximately one year ago, he noted elevations appearing across the area of the right cheek where the discoid lupus erythematosus had previously caused minimal atrophic changes of the skin.At the initial examination, the patient had five different excrescences on this area of the right cheek. The one just in front of the right ear appeared to be a clinically classical keratoacanthoma (Figure) and this was borne out on biopsy.Just in front of this were two elevated, 5-mm crusted scaly areas which looked like either hypertrophic lupus erythematosus or keratosis. These proved to be inflamed keratoses. Further towards the midline and adjacent

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