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November 1967

Pemphigus Vulgaris and Pulmonary Nocardiosis

Author Affiliations

New York

From the Department of Dermatology, College of Physicians and Surgeons, Columbia University, and the Dermatology Service of the Presbyterian Hospital, New York.

Arch Dermatol. 1967;96(5):548-551. doi:10.1001/archderm.1967.01610050070011

A patient with progressive pemphigus vulgaris, while being treated with high dosage corticosteroid therapy, developed pulmonary nocardiosis. She was successfully treated with sulfisoxazole and catheter pulmonary drainage, while corticosteroid therapy was maintained and slowly lowered with improvement of the pemphigus.

The subject of nocardiosis and nocardial infections complicating pemphigus is reviewed. The diagnosis of nocardiosis is of great importance because high and prolonged dosage with sulfonamides is curative in a significant percentage of cases.

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