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December 1967

Calcinosis Cutis Following Intralesional Injection of Triamcinolone Hexacetonide

Arch Dermatol. 1967;96(6):689-691. doi:10.1001/archderm.1967.01610060083014

Calcinosis cutis was observed in a patient with nummular eczema following the intralesional injection of triamcinolone hexacetonide. X-ray diffraction analysis indicated that the calcium was deposited as hydroxyapatite crystals. Following decalcification of a deposit, an x-ray diffraction pattern was obtained which was similar to the original steroid. This suggested that the calcified deposit contained a steroid derived from the triamcinolone hexacetonide.