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April 1968

Sclerema Neonatorum: Report of Case and Analysis of Subcutaneous and Epidermal-Dermal Lipids by Chromatographic Methods

Author Affiliations

Portland, Ore

From the Division of Dermatology, University of Oregon Medical School, Portland, Ore.

Arch Dermatol. 1968;97(4):372-380. doi:10.1001/archderm.1968.01610100012002

A case report of an infant who died with sclerema neonatorum is presented. A detailed biochemical study revealed an unusually high ratio of saturated to unsaturated fatty acids (56.8:43.2) in the subcutaneous triglycerides of the sclerematous infant. Oleic (C18:1) acid was present in normal amounts. Several alternative hypotheses for explaining the sclerematous process are discussed.

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