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August 1968

Malignant Tumors as a Late Complication of Vaccination

Author Affiliations

Burbank, Calif; London

From Burbank, Calif (Dr. Reed) and the Department of Histopathology, St. John's Hospital for Diseases of the Skin, London (Dr. Wilson-Jones).

Arch Dermatol. 1968;98(2):132-135. doi:10.1001/archderm.1968.01610140030005

Four basal and one squamous cell carcinomas and a single instance of a malignant melanoma arising in vaccination scars have occurred in five southern California patients. Sun exposure on a previously scarred skin was the main etiological factor in the development of the basal and squamous cell tumors. Sun exposure was probably unimportant in the case of the melanoma because of the short time interval between vaccination and the development of the tumor.

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