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September 1968

Idiopathic Lipograulomatous Hypodermitis

Arch Dermatol. 1968;98(3):290-298. doi:10.1001/archderm.1968.01610150076015

The conditions classically known as Darier-Roussy's hypodermal sarcoid, Bazin's erythema induratum, nodular vasculitis, Weber-Christian's panniculitis, and Makai's subcutaneous lipogranulomatosis are nothing but variants of one fundamental entity which the authors propose naming "idiopathic lipogranulomatous hypodermitis." This proposal is based on the clinical manifestations, pathology, and evolution of numerous cases followed up during many years.

The so-called "periarteritis nodosa cutis" is only a clinical form of nodular vasculitis (or chronic relapsing micronodular hypodermitis). However, there exists an authentic cutaneous periarteritis nodosa.

Darier-Roussy's hypodermal sarcoid should not be classified together with Boeck-Besnier-Schumann's sarcoidosis.

Makai's subcutaneous lipogranulomatosis is a special form observed in children and should not be considered separately from the so-called Rothmann-Makai syndrome.