Porphyria Cutanea Tarda. Presented by Charles P. DeFeo, MD.
A 27-year-old white man had noted for the past four to six months increased hair growth across both temples, extending into the lateral portion of his eyebrows and the upper portion of his cheeks. He also noted increased pigmentation over this area and across his forehead. The family history is noncontributory and he has been in good health all his life.
Laboratory Data.—
Total urinary porphyrins were 3,042μg in two 24-hour specimens ( normal, less than 100 μg); glucose tolerance test: fasting, 76 mg/100 cc; one half hour, 116 mg/100 cc; one hour, 102 mg/100 cc; two hours, 62 mg/100 cc; three hours, 59 mg/100 cc; four hours, 46 mg/100 cc; urinalysis normal; routine blood count normal; hematocrit, 48%; sulfobromophthalein, (BSP), 4.8% retention; serum iron, 170μg/100 cc (normal, 80 to 180); iron binding capacity, 390μg/100 cc (normal 250 to 430). Wood's light