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February 1969

Childhood Pemphigus Vulgaris: Report of a Case

Author Affiliations

Rochester, Minn; Buffalo, NY; Rochester, Minn

From Mayo Graduate School of Medicine (University of Minnesota), Rochester, Minn (Dr. Jordon); State University of New York at Buffalo, School of Medicine (Dr. Ihrig); and Mayo Clinic and Mayo Foundation, Section of Dermatology, Rochester, Minn (Dr. Perry).

Arch Dermatol. 1969;99(2):176-179. doi:10.1001/archderm.1969.01610200048008

Pemphigus vulgaris rarely occurs in childhood. The history of a patient, 13 years of age, is reported. Evidence of the disease was established in this patient by the presence of acantholytic cells in a surprabasal position shown by usual histologic techniques and was confirmed further by the demonstration of intercellular fluorescence made possible with newer immunofluorescent tests available today. Pemphigus vulgaris pursues a severe malignant course in this age group. Therefore, prompt diagnosis and early initiation of aggressive therapy with adrenocorticosteroids is warranted.

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