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March 1969


Author Affiliations

Assistant Professor of Medicine University of Maryland Baltimore 21201

Arch Dermatol. 1969;99(3):365. doi:10.1001/archderm.1969.01610210119024

To the Editor.—  Recent isolation of specific virus has stimulated further clinical investigation of rubella. An erythematous macular exanthem lasting three to four days appears early in this infection. There is no report in the literature of the histology of the exanthem observed in patients proven to have rubella. Castrow and DeBeukelaer, reported only nonspecific dermal inflammatory changes in their patient with congenital rubella syndrome.1 Six patients with rubella were examined by me during the 1964 Massachusetts epidemic. All patients were in their early 20's and had an exanthem of 6 to 48 hours duration. One individual had petechiae and another developed transitory polyarthralgia. No other complications were observed. Specific virus was isolated from the blood in all cases and the throat in four.2 Neutralization tests were done on two patients and found to be positive. Punch biopsy specimens of volar forearm skin were performed. No inclusion bodies

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