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April 1969

Influence of Oral Prednisone on Eczematous Patch Test Reactions

Author Affiliations

New Orleans

From the Department of Dermatology, Louisiana State University School of Medicine, New Orleans.

Arch Dermatol. 1969;99(4):380-389. doi:10.1001/archderm.1969.01610220008002

The effect of systemic corticosteroid therapy on eczematous patch test reactions was studied in 20 subjects. Fourteen subjects continued to develop positive reactions to standard concentrations of allergens while receiving a daily oral dose of 40 mg prednisone. In six other subjects strongly positive patch test reactions were reversed during treatment with prednisone. Other evidence of corticosteroid effect included changing patterns of reaction to a series of graded dilutions of allergens and the delayed appearance of positive reactions in some subjects.