Lesions of disseminated superficial actinic porokeratosis (DSAP) were experimentally produced following prolonged artificial ultraviolet light radiation. DSAP, a genodermatosis with an autosomal dominant mode of inheritance, is disseminated primarily on sun exposed areas of the skin of adults, the largest number of lesions being on the extremities. Lesions often increase in number and become more prominent during summer months when sun exposure is great.
It is important that DSAP be distinguished from porokeratosis of Mibelli because some lesions of DSAP mimic precancerous actinic keratoses and other conditions. DSAP is also more common in occurrence in some geographic areas with increased levels of sunlight.
Chernosky ME, Anderson DE. Disseminated Superficial Actinic PorokeratosisClinical Studies and Experimental Production of Lesions. Arch Dermatol. 1969;99(4):401–407. doi:10.1001/archderm.1969.01610220029005
Customize your JAMA Network experience by selecting one or more topics from the list below.